Strategies for immortalization of primary hepatocytes
نویسندگان
چکیده
منابع مشابه
Strategies for immortalization of primary hepatocytes.
The liver has the unique capacity to regenerate in response to a damaging event. Liver regeneration is hereby largely driven by hepatocyte proliferation, which in turn relies on cell cycling. The hepatocyte cell cycle is a complex process that is tightly regulated by several well-established mechanisms. In vitro, isolated hepatocytes do not longer retain this proliferative capacity. However, in...
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ژورنال
عنوان ژورنال: Journal of Hepatology
سال: 2014
ISSN: 0168-8278
DOI: 10.1016/j.jhep.2014.05.046